https://www.ceesdekker.net Secrets

https://www.ceesdekker.net Secrets

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‘Indeed, that is definitely about suitable. I try to find a Actual physical idea of Organic programs inside of a base-up way. I feel you could possibly distinguish 3 traces of study in my group for the time being. The initial issues chromosome structure: How does one receive a metre-very long DNA polymer folded and organised in this type of microscopic cell? We have developed visualisation procedures that allow for us to check how, one example is, SMC proteins loop DNA (movie on Youtube) as a way to Develop up chromosomes.

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The subsequent article content are merged in Scholar. Their combined citations are counted only for the very first write-up.

Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metallic clusters

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style in 2005. (nl)

Instance (3) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in grey, the rim on the pore is highlighted in purple, and also a 3D rendering with the movement with the DNA rod is exhibited.

Since 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA fix proteins to DNA translocation through nanopores. Recently his exploration has focused on learning mobile division with microorganisms on chip, although his ultimate desire is inside the direction of knowing synthetic cells.

Atomic power microscopy displays that vaccinia topoisomerase IB generates filaments on DNA in a cooperative style

Understanding fundamental processes regulating the spatial and dynamic organisation from the DNA in Reside cells.

At the moment, we also realized that it should be feasible to make use of just one semiconducting carbon nanotube to create a transistor — and we set out to really make it. We stretched unique semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate as being a gate electrode, establishing The essential a few-terminal format of a field-outcome transistor (Fig.

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2001, discovery of solitary-electron transistors at space temperature based upon nanotubes; realization of initial logic circuits with carbon nanotube equipment; and discovery in the molecular composition ceesdekker.net of DNA fix enzymes with AFM

Let’s initially search back in the intervening time once you decided to change your concentrate from superconductivity and nanotubes to biology at the conclusion of the 1990s.

2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of the mechanical Houses of double-stranded RNA; and initial one-molecule research of DNA translocation by a restriction-modification enzyme.